Let , and denote its set of zeros by
, where
consists of the nontrivial zeros of
and
those of the prefactor
, with
. We introduce a non-symmetric operator
on
with spectrum
Assuming simplicity of all nontrivial Riemann zeros, we construct the compression of
to the spectral subspace associated with
, and show that
is intertwined with its adjoint by a positive semidefinite operator
; i.e.,
with
. The positivity of
, viewed as an operator-theoretic form of (Bombieri’s refinement of) Weil’s positivity criterion, enforces
for all
, in accordance with the Riemann Hypothesis. Under the same positivity condition, the intertwining relation yields a self-adjoint operator whose spectrum coincides with the set
. We further extend the framework to accommodate higher-order nontrivial Riemann zeros, should they exist, and to cover any Mellin-transformable
-function satisfying a functional equation.